Article Dans Une Revue United European Gastroenterology Journal Année : 2025

European Guideline on Chronic Nausea and Vomiting—A UEG and ESNM Consensus for Clinical Management

1 Digestive System Research Unit, Hospital General Vall d'Hebron, Autonomous University of Barcelona, Barcelona, Spain.
2 Israelitic Hospital, Academic Hospital University of Hamburg, Hamburg, Germany.
3 Wingate Institute of Neurogastroenterology
4 UZ Leuven - Universitair Ziekenhuis Leuven = University Hospital of Leuven = Hopital universitaire de Louvain
5 Department of Gastroenterology and Hepatology, Wroclaw Medical University, Wroclaw, Poland.
6 Freie Universität Berlin = Free University of Berlin
7 Digestive System Research Unit, Vall d'Hebron University Hospital, Barcelona, Spain.
8 Mech-Sense & Centre for Pancreatic Diseases, Department of Gastroenterology & Hepatology, Aalborg University Hospital, Aalborg, Denmark.
9 GU - Göteborgs Universitet = University of Gothenburg
10 Stress et Interactions Neuro-Digestives, Grenoble Institut des Neurosciences, Centre de Recherche INSERM 836 UJF-CEA-CHU, Grenoble, France.
11 Second Department of Internal Medicine and Gastroenterology, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.
12 Maastricht UMC+ - Maastricht University Medical Center+
13 Neurogastroenterology and Motility Unit, Gastroenterology Department, Institut Clínic de Malalties Digestives i Metabòliques Hospital Clinic of Barcelona, Barcelona, Spain.
14 Department of Gastroenterology and Hepatology, University Hospitals Leuven, Leuven, Belgium.
15 CHU Bordeaux - Centre Hospitalier Universitaire de Bordeaux
16 CIC Bordeaux
17 Unipd - Università degli Studi di Padova = University of Padua
18 Department of Gastroenterology, Clinical Hospital Centre of Rijeka, Faculty of Medicine University of Rijeka, Rijeka, Croatia.
19 ADEN - Nutrition, Inflammation et axe Microbiote-Intestin-Cerveau
20 IRIB - Institute for Research and Innovation in Biomedicine
21 UNIROUEN - Université de Rouen Normandie
22 Service de Physiologie Digestive, Urinaire, Respiratoire et de l'Exercice [CHU Rouen]
23 Division of Gastroenterology and Hepatology, Department of Internal Medicine, Medical University of Graz, Graz, Austria.
24 University of Sheffield [Sheffield]
25 Health Center Zagreb-West, Zagreb, Croatia.
26 La Mina Primary Care Academic Health Centre, Catalan Institute of Health, University of Barcelona, Barcelona, Spain.
27 Department of Pediatric Gastroenterology, Great Ormond Street Hospital, London, UK.
28 Department of Gastroenterology and Hepatology, Medical University of Silesia, Katowice, Poland.
29 Department of Internal Medicine and Gastroenterology, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.
30 NIHR Nottingham Biomedical Research Centre (BRC), Nottingham University Hospitals NHS Trust and the University of Nottingham, Nottingham, UK.
31 Department of Neurosciences, Deglutology, Experimental Otorhinolaryngology (ExpORL), University of Leuven, Leuven, Belgium.
32 Department of Gastroenterology, The Wellington Hospital, London, UK.
33 Department of Translational Medicine, University of Ferrara, Ferrara, Italy.
34 Second Department of Internal Medicine and Gastroenterology, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.
Imran Aziz

Résumé

ABSTRACT Introduction Chronic nausea and vomiting are symptoms of a wide range of gastrointestinal and non‐gastrointestinal conditions. Diagnosis can be challenging and requires a systematic and well‐structured approach. If the initial investigation for structural, toxic and metabolic disorders is negative, digestive motility and gut‐brain interaction disorders should be assessed. United European Gastroenterology (UEG) and the European Society for Neurogastroenterology and Motility (ESNM) identified the need for an updated, evidence‐based clinical guideline for the management of chronic nausea and vomiting. Methods A multidisciplinary team of experts in the field, including European specialists and national societies, participated in the development of the guideline. Relevant questions were addressed through a literature review and statements were developed and voted on according to a Delphi process. Results Ninety‐eight statements were identified and voted following the Delphi process. Overall agreement was high, although the grade of scientific evidence was low in many areas. Disagreement was more evident for some pharmacological treatment options. A diagnostic algorithm was developed, focussing on the differentiating features between gastrointestinal motility and gut‐brain interaction disorders with predominant nausea and vomiting. Conclusion These guidelines provide an evidence‐based framework for the evaluation and treatment of patients with chronic nausea and vomiting.

Dates et versions

hal-04932466 , version 1 (06-02-2025)

Identifiants

Citer

Carolina Malagelada, Jutta Keller, Daniel Sifrim, Jordi Serra, Jan Tack, et al.. European Guideline on Chronic Nausea and Vomiting—A UEG and ESNM Consensus for Clinical Management. United European Gastroenterology Journal, 2025, 5 (1), pp.21. ⟨10.1002/ueg2.12711⟩. ⟨hal-04932466⟩
121 Consultations
0 Téléchargements

Altmetric

Partager

  • More