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Collection HAL du laboratoire INSERM UMR 1073
The works of our group are mainly dedicated to the study of eating disorders, irritable bowel syndrome (IBS) and inflammatory bowel diseases (IBD). These pathologies share common features of intestinal dysbiosis, inflammation and dysregulation of the gut-brain axis and offer great opportunities for innovative therapeutic strategies (immunonutrition, neurostimulation). Our investigations explore the underlying mechanisms of these diseases from the molecular level to clinical trials. This broad range of research from the bench to the bedside is the result of our research strategy that brings together basic and clinical sciences, in a tight collaboration between laboratory scientists and health professionals. Our dynamic research team has an active research strategy, which also drives the translation of research from the laboratory to patenting and creation of biotech companies entrepreneurship.
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Nos dernières publications
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Romain Legrand, Nicolas Lucas, Manon Dominique, Saïda Azhar, Camille Deroissart, et al.. Commensal Hafnia alvei strain reduces food intake and fat mass in obese mice—a new potential probiotic for appetite and body weight management. International Journal of Obesity, 2020, ⟨10.1038/s41366-019-0515-9⟩. ⟨hal-02474510⟩
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Colin Salaün, Marine Courvalet, Léna Rousseau, Kévin Cailleux, Jonathan Breton, et al.. Sex-dependent circadian alterations of both central and peripheral clock genes expression and gut–microbiota composition during activity-based anorexia in mice. Biology of Sex Differences, 2024, 15 (1), pp.6. ⟨10.1186/s13293-023-00576-x⟩. ⟨hal-04441465⟩
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Marc Bénard, France Bellisle, Chantal Julia, Valentina A. Andreeva, Fabrice Etilé, et al.. Impulsivity is associated with food intake, snacking, and eating disorders in a general population. The American Journal of Clinical Nutrition, 2019, 109 (1), pp.117-126. ⟨10.1093/ajcn/nqy255⟩. ⟨halshs-02096511⟩
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Margaux Robert, Camille Buscail, Benjamin Allès, Rébecca Shankland, Marie-Pierre Tavolacci, et al.. Dispositional optimism is associated with weight status, eating behavior, and eating disorders in a general population‐based study. International Journal of Eating Disorders, 2020, 53 (10), ⟨10.1002/eat.23347⟩. ⟨hal-02931727⟩
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C. Desprez, N. Turmel, C. Chesnel, S. Sheikh Ismael, M. Tamiatto, et al.. Fecal incontinence subtype assessment (FI-SA): a new tool to distinguish among subtypes of fecal incontinence in a neurogenic population. Clinics and Research in Hepatology and Gastroenterology, 2022, pp.101900. ⟨10.1016/j.clinre.2022.101900⟩. ⟨hal-03615441⟩
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Ludovic Langlois, Sarah Oddoux, Kanhia Aublé, Paul Violette, Pierre Déchelotte, et al.. Effects of Glutamine, Curcumin and Fish Bioactive Peptides Alone or in Combination on Intestinal Permeability in a Chronic-Restraint Stress Model. International Journal of Molecular Sciences, 2023, 24 (8), pp.7220. ⟨10.3390/ijms24087220⟩. ⟨hal-04103913⟩