Gastric electrical stimulation is safe during pregnancy and delivery: Results from a French cohort - Normandie Université Accéder directement au contenu
Article Dans Une Revue Neurogastroenterology & Motility Année : 2023

Gastric electrical stimulation is safe during pregnancy and delivery: Results from a French cohort

Résumé

Abstract Background Gastric electrical stimulation (GES) is an effective therapy in medically refractory chronic nausea and vomiting. GES is assumed to be a contraindication for pregnancy. We examined the safety of GES during pregnancy and its clinical impact on vomiting symptoms. Methods A retrospective study was performed in two tertiary centers including all female patients of childbearing age implanted with GES. Patients without pregnancy while on GES were asked about their desire and concerns about pregnancy. Patients who were pregnant while on GES therapy were interviewed about the course of the pregnancy and labor, as well as the health of the children. Key Results Among 91 patients implanted at childbearing age, 54 patients without pregnancy answered the questionnaire. Nine patients (16.7%) reported a desire for pregnancy and five patients (7.4%) reported worries about the safety of GES during pregnancy. Sixteen pregnancies were reported in 10 patients. All pregnancies ended in a live birth with premature birth in 12 pregnancies (75.0%). No health concern was currently noted in these children. No severe GES‐related complications occurred during pregnancy with only pain at the implantation site reported during 3 pregnancies (18.8%). The severity and frequency of nausea and vomiting significantly increased during the first trimester ( p = 0.04 and p = 0.005, respectively) and decreased after the delivery, becoming lower than before the pregnancy ( p = 0.044 and p = 0.011, respectively). Conclusion & Inferences Patients are concerned regarding pregnancy while being treated with GES. No serious maternal or fetal complications related to GES were noted in our cohort.
Fichier principal
Vignette du fichier
Neurogastroenterology Motil - 2023 - Soliman - Gastric electrical stimulation is safe during pregnancy and delivery .pdf (960.93 Ko) Télécharger le fichier
Origine Fichiers éditeurs autorisés sur une archive ouverte

Dates et versions

hal-04206379 , version 1 (29-05-2024)

Licence

Identifiants

Citer

Heithem Soliman, Martha Schalla, Benoît Coffin, Guillaume Gourcerol. Gastric electrical stimulation is safe during pregnancy and delivery: Results from a French cohort. Neurogastroenterology & Motility, 2023, 35 (10), pp.e14657. ⟨10.1111/nmo.14657⟩. ⟨hal-04206379⟩
14 Consultations
2 Téléchargements

Altmetric

Partager

Gmail Mastodon Facebook X LinkedIn More