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Journal Articles Advanced Synthesis and Catalysis Year : 2021

Multicomponent Catalytic Enantioselective Synthesis of Isoxazolidin‐5‐Ones

Abstract

We report herein a strategy to afford a multicomponent catalytic enantioselective synthesis of βsubstituted isoxazolidin-5-ones via a KMC process promoted by a suited cupreine used as bifunctional organocatalyst. The hydroxamic acid component, with a sterically hindered amide moiety, proved to be key for the successful formation and transformation of the obtained original N-amide isoxazolidin-5-ones.
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Dates and versions

hal-03322422 , version 1 (19-08-2021)

Identifiers

Cite

Julien Annibaletto, Thomas Martzel, Vincent Levacher, Sylvain Oudeyer, Jean-François Brière. Multicomponent Catalytic Enantioselective Synthesis of Isoxazolidin‐5‐Ones. Advanced Synthesis and Catalysis, 2021, 363, pp.4447-4451. ⟨10.1002/adsc.202100719⟩. ⟨hal-03322422⟩
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