Multicentric Analysis of the Species Distribution and Antifungal Susceptibility of Cryptic Isolates from Aspergillus Section Fumigati - Normandie Université Access content directly
Journal Articles Antimicrobial Agents and Chemotherapy Year : 2020

Multicentric Analysis of the Species Distribution and Antifungal Susceptibility of Cryptic Isolates from Aspergillus Section Fumigati

S. Imbert
  • Function : Author
A. C Normand
  • Function : Author
S. Cassaing
  • Function : Author
F. Gabriel
  • Function : Author
L. Kristensen
  • Function : Author
C. Bonnal
  • Function : Author
J. Guitard
  • Function : Author
L. Hasseine
  • Function : Author
M. Palous
  • Function : Author
M. Piarroux
  • Function : Author
M. Hendrickx
  • Function : Author
R. Piarroux
  • Function : Author
A. Fekkar
  • Function : Author
Costa D Guitard
  • Function : Author

Abstract

ABSTRACT The antifungal susceptibility of Aspergillus cryptic species is poorly known. We assessed 51 isolates, belonging to seven Fumigati cryptic species, by the EUCAST reference method and the concentration gradient strip (CGS) method. Species-specific patterns were observed, with high MICs for azole drugs, except for Aspergillus hiratsukae and Aspergillus tsurutae , and high MICs for amphotericin B for Aspergillus lentulus and Aspergillus udagawae . Essential and categorical agreements between EUCAST and CGS results were between 53.3 and 93.3%.
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Dates and versions

hal-03238921 , version 1 (28-05-2021)

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S. Imbert, A. C Normand, S. Cassaing, F. Gabriel, L. Kristensen, et al.. Multicentric Analysis of the Species Distribution and Antifungal Susceptibility of Cryptic Isolates from Aspergillus Section Fumigati. Antimicrobial Agents and Chemotherapy, 2020, 64 (12), ⟨10.1128/AAC.01374-20⟩. ⟨hal-03238921⟩
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