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Journal Articles Annals of Surgery Year : 2015

A Step Toward NOTES Total Mesorectal Excision for Rectal Cancer


Background: Previous publications have suggested that endoscopic transanal proctectomy (ETAP) is a promising technique and may be an alternative to conventional low anterior resection for rectal cancer. The aim of this study was to evaluate the technical feasibility of ETAP, with a particular focus on postoperative and oncological results and on functional outcomes. Methods: This study was a multicenter prospective study of unselected consecutive patients with low rectal cancer requiring proctectomy and coloanal anastomosis. All patients underwent a standardized procedure. The study endpoints were the safety and adequacy of the oncological resection criteria. All patients were evaluated with the Wexner Fecal Incontinence Questionnaire after stoma closure. Results: Fifty-six consecutive patients (41 men) underwent ETAP between February 2010 and June 2012. The median age was 65 years (39–83), and the median body mass index was 27 (20-42). No intraoperative complications were encountered. There was no postoperative mortality, and the morbidity rate was 26%. The mesorectum was complete in 47 cases (84%) and nearly complete in 9 cases (16%). The median number of lymph nodes retrieved was 12 (range, 7–29) per patient. The median radial and distal margins were 8 mm (0–20) and 10 mm (3–40), respectively. R0 resection was achieved in 53 patients (94.6%). The median Wexner score was 4 (3–12). Thirteen (28%) patients reported stool fragmentation and difficult evacuation. Conclusions: ETAP is a feasible alternative surgical option to conventional laparoscopy for rectal resection and may represent a promising step toward rectal natural orifice transluminal endoscopic surgery (NOTES).
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hal-02372765 , version 1 (20-11-2019)





Jean-Jacques Tuech, Mehdi Karoui, Bernard Lelong, Cécile de Chaisemartin, Valérie Bridoux, et al.. A Step Toward NOTES Total Mesorectal Excision for Rectal Cancer. Annals of Surgery, 2015, 261 (2), pp.228-233. ⟨10.1097/SLA.0000000000000994⟩. ⟨hal-02372765⟩
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