Panorama of limbal changes - Normandie Université Access content directly
Journal Articles Journal Français d'Ophtalmologie Year : 2019

Panorama of limbal changes

Abstract

The corneal limbus is a privileged region on the border between two quite different microenvironments, where corneal epithelial stem cells, numerous melanocytes, and antigen-presenting cells are all concentrated within a richly vascularized and innervated stroma. This situation within the ocular surface confers on it the key functions of barrier, epithelial renewal and defense of the cornea. As an immunological crossroads and since the corneoscleral limbus is directly exposed to external insults such as caustic agents, ultraviolet radiation, microbial agents, and allergens, it is the potential site of many tumoral, degenerative or inflammatory pathologies and may progress under certain conditions to limbal stem cell deficiency.
Fichier principal
Vignette du fichier
S0181551219300373.pdf (8.81 Mo) Télécharger le fichier
Origin : Files produced by the author(s)

Dates and versions

hal-02316571 , version 1 (22-10-2021)

Licence

Attribution - NonCommercial

Identifiers

Cite

J. Gueudry, F. Majo, A. Delcampe, M. Muraine. Panorama of limbal changes. Journal Français d'Ophtalmologie, 2019, 42 (3), pp.e83-e94. ⟨10.1016/j.jfo.2019.02.001⟩. ⟨hal-02316571⟩
42 View
22 Download

Altmetric

Share

Gmail Facebook Twitter LinkedIn More