Article Dans Une Revue Tetrahedron Année : 2009

Original TDAE strategy using α-halocarbonyl derivatives

Résumé

We report herein the selective C–C bond formation by the reaction of nitrobenzyl carbanions, formed via the TDAE strategy, with a-haloesters and a-haloamides. This reaction, extended in benzodioxole and dimethoxybenzene series provides new potentially CNS active agents.

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Dates et versions

hal-05577598 , version 1 (02-04-2026)

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Marc Since, Thierry Terme, Patrice Vanelle. Original TDAE strategy using α-halocarbonyl derivatives. Tetrahedron, 2009, 65 (31), pp.6128-6134. ⟨10.1016/j.tet.2009.05.036⟩. ⟨hal-05577598⟩
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