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Article Dans Une Revue Chemistry - A European Journal Année : 2024

Nickel‐Catalyzed Intramolecular Hydrosilylation of Alkynes: Embracing Conventional and Electrochemical Routes

Résumé

Abstract Nickel‐catalyzed intramolecular hydrosilylation can be efficiently achieved with high regio‐ and stereoselectivities through two distinct methodologies. The first approach utilizes a conventional method, involving the reduction of nickel salt (NiBr 2 ‐2,2’‐bipyridine) using manganese metal. The second method employs a one‐step electrochemical reaction, utilizing the sacrificial anode process and NiBr 2 bipy catalysis. Both methods yield silylated heterocycles in good to high yields through a syn ‐ exo ‐ dig cyclization process. Control experiments and molecular electrochemistry (cyclic voltammetry) provided further insights into the reaction mechanism.

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Chimie organique
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hal-04592646 , version 1 (29-05-2024)

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Mathias Reboli, Seydou Kassamba, Muriel Durandetti. Nickel‐Catalyzed Intramolecular Hydrosilylation of Alkynes: Embracing Conventional and Electrochemical Routes. Chemistry - A European Journal, 2024, 30, pp.e202400440. ⟨10.1002/chem.202400440⟩. ⟨hal-04592646⟩
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