Photocatalyzed Hydroaminodifluoroalkylation of Alkenes - Normandie Université Accéder directement au contenu
Article Dans Une Revue Chemistry - A European Journal Année : 2023

Photocatalyzed Hydroaminodifluoroalkylation of Alkenes

Résumé

Abstract The synthesis of undescribed β‐aminodifluoroethylsulfinates and their uses in the hydroaminodifluoroalkylation of alkenes is reported. This reaction is performed in the presence of a photocatalyst (4CzIPN, Ru complexes) and enables the direct incorporation of a β‐difluoroamine moiety into vinylic aryls, unactivated alkenes, and electron‐rich, or ‐deficient alkenes. The mechanism was studied, and the formation of a gem ‐difluoromethyl radical was observed after the selective oxidation of the sulfinate function.

Domaines

Chimie
Fichier non déposé

Dates et versions

hal-04391583 , version 1 (15-01-2024)

Identifiants

Citer

Pierre Fossé, Emmanuel Pfund, Thierry Lequeux. Photocatalyzed Hydroaminodifluoroalkylation of Alkenes. Chemistry - A European Journal, 2023, 29 (56), ⟨10.1002/chem.202301793⟩. ⟨hal-04391583⟩
9 Consultations
2 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More