Equine gammaherpesviruses: Pathogenesis, epidemiology and diagnosis - Normandie Université Accéder directement au contenu
Article Dans Une Revue Veterinary Journal Année : 2010

Equine gammaherpesviruses: Pathogenesis, epidemiology and diagnosis

Résumé

Equine gammaherpesviruses (γEHV) have been widely studied over the past 45 years and many isolates have been characterised. Despite this, the diagnosis of γEHV infection remains difficult to establish as its clinical manifestations lack specificity, ranging from mild respiratory signs in a small number of animals to outbreaks in large groups of young horses. This review focuses on the epidemiology, pathogenesis, clinical manifestations and diagnosis of equine herpesvirus (EHV)-2 and -5 infections, as well as on the genetic variation of these viruses. Study of these variations has resulted in hypotheses relating to viral re-infection and re-activation. Interestingly, the viruses were found to contain genetic sequences identical to those of eukaryotic cells which are considered central to the development of viral latency through interfering with host immune and inflammatory responses. Future molecular biological studies will further elucidate the virulence mechanisms of these equine pathogens.

Dates et versions

hal-04223084 , version 1 (29-09-2023)

Identifiants

Citer

Guillaume Fortier, Emmanuelle van Erck, Stéphane Pronost, Pierre Lekeux, Etienne Thiry. Equine gammaherpesviruses: Pathogenesis, epidemiology and diagnosis. Veterinary Journal, 2010, 186 (2), pp.148-156. ⟨10.1016/j.tvjl.2009.08.017⟩. ⟨hal-04223084⟩

Collections

COMUE-NORMANDIE
9 Consultations
0 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More