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Article Dans Une Revue ESMO Open Année : 2023

Impact of EGFRA289T/V mutation on relapse pattern in glioblastoma

O. Langlois
  • Fonction : Auteur

Résumé

Molecular factors influence relapse patterns in glioblastoma. The hotspot mutation located at position 289 of the extracellular domain of the epidermal growth factor receptor (EGFRA289mut) is associated with a more infiltrative phenotype. The primary objective of this study was to explore the impact of the EGFRA289 mutation on the pattern of relapse after chemoradiotherapy-based treatment of patients suffering from newly diagnosed glioblastoma.

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hal-04174989 , version 1 (01-08-2023)

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A. Noeuveglise, N. Sarafan-Vasseur, L. Beaussire, F. Marguet, R. Modzelewski, et al.. Impact of EGFRA289T/V mutation on relapse pattern in glioblastoma. ESMO Open, 2023, 8 (1), pp.100740. ⟨10.1016/j.esmoop.2022.100740⟩. ⟨hal-04174989⟩
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