Organocatalytic enantioselective synthesis of β-amino sulfonic acid derivatives
Résumé
An unprecedented enantioselective conjugate addition reaction of sodium bisulfite to various nitrostyrenes occurred upon the influence of a bifunctional amino-thiourea organocatalyst; a strategy that opens a straightforward route to unprotected chiral taurine derivatives thanks to the reduction of the obtained β-nitroethanesulfonic acids into the corresponding amino derivatives.
Origine | Fichiers produits par l'(les) auteur(s) |
---|