A convenient synthesis of N-boc protected primary amines via the reaction of organoboranes with Li or K t-butyl-N-tosyloxycarbamate - Normandie Université Access content directly
Journal Articles Tetrahedron Letters Year : 1992

A convenient synthesis of N-boc protected primary amines via the reaction of organoboranes with Li or K t-butyl-N-tosyloxycarbamate

Abstract

Primary and secondary alkylboranes reacted rapidly at low temperature with Li or K t-butyl-N-tosyloxycarbamate (LiBTOC or KBTOC) to give the corresponding N-Boc protected primary amines in modest to good yields (16–81%). N-Boc primary amines were obtained from the reaction of alkylboranes with Lithium or Potassium salts of t-butyl-N-tosyloxycarbamate.

Dates and versions

hal-02385498 , version 1 (28-11-2019)

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Cite

Jean-Pierre Genet, Josef Hajicek, Laurent Bischoff, Christine Greck. A convenient synthesis of N-boc protected primary amines via the reaction of organoboranes with Li or K t-butyl-N-tosyloxycarbamate. Tetrahedron Letters, 1992, 33 (19), pp.2677-2680. ⟨10.1016/S0040-4039(00)79055-1⟩. ⟨hal-02385498⟩
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