Regioselective opening of N-Cbz glutamic and aspartic anhydrides with carbon nucleophiles - Normandie Université Access content directly
Journal Articles Tetrahedron: Asymmetry Year : 2006

Regioselective opening of N-Cbz glutamic and aspartic anhydrides with carbon nucleophiles

Abstract

Depending on the experimental conditions, aspartic and glutamic anhydrides can be opened regioselectively with Grignard reagents, thus giving access to different isomers of chiral amino-ketoesters.

Dates and versions

hal-02385048 , version 1 (28-11-2019)

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Geoffrey Deguest, Laurent Bischoff, Corinne Fruit, Francis Marsais. Regioselective opening of N-Cbz glutamic and aspartic anhydrides with carbon nucleophiles. Tetrahedron: Asymmetry, 2006, 17 (14), pp.2120-2125. ⟨10.1016/j.tetasy.2006.07.039⟩. ⟨hal-02385048⟩
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