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Conference Papers Year : 2019

Glioblastoma migration along constraints with different geometries: how to mimick brain parenchyma invasion?

Abstract

A microfluidic device is demonstrated to analyze glioblastoma migration along constraints with precisely designed geometries. This in-vitro model reveals physiologically relevant glioma invasion scenarios: full migration along constraints, suspended motion by extreme constriction, and limited migration associated with the ejection of plasma membrane particles due to the continuing extension.
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Dates and versions

hal-02303630 , version 1 (15-11-2019)

Identifiers

  • HAL Id : hal-02303630 , version 1

Cite

Mehmet Tarhan, Alexandre Mutel, Laurence Desrues, Dominique Collard, Hélène Castel. Glioblastoma migration along constraints with different geometries: how to mimick brain parenchyma invasion?. The 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS 2019), Oct 2019, Basel, Switzerland. ⟨hal-02303630⟩
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