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Journal Articles Molecular and Cellular Endocrinology Year : 2010

Pineal function: Impact of microarray analysis


Microarray analysis has provided a new understanding of pineal function by identifying genes that are highly expressed in this tissue relative to other tissues and also by identifying over 600 genes that are expressed on a 24-h schedule. This effort has highlighted surprising similarity to the retina and has provided reason to explore new avenues of study including intracellular signaling, signal transduction, transcriptional cascades, thyroid/retinoic acid hormone signaling, metal biology, RNA splicing, and the role the pineal gland plays in the immune/inflammation response. The new foundation that microarray analysis has provided will broadly support future research on pineal function.

Dates and versions

hal-02279788 , version 1 (05-09-2019)



David Klein, Michael Bailey, David Carter, Jong-So Kim, Qiong Shi, et al.. Pineal function: Impact of microarray analysis. Molecular and Cellular Endocrinology, 2010, 314 (2), pp.170-183. ⟨10.1016/j.mce.2009.07.010⟩. ⟨hal-02279788⟩
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