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Journal Articles Annual Review of Pharmacology and Toxicology Year : 2005

Actions of adenosine at its receptors in the CNS insights from knockouts and drugs

Abstract

Adenosine and its receptors have been the topic of many recent reviews. These reviews provide a good summary of much of the relevant literature--including the older literature. We have, therefore, chosen to focus the present review on the insights gained from recent studies on genetically modified mice, particularly with respect to the function of adenosine receptors and their potential as therapeutic targets. The information gained from studies of drug effects is discussed in this context, and discrepancies between genetic and pharmacological results are highlighted.
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Dates and versions

hal-02185481 , version 1 (16-07-2019)

Identifiers

  • HAL Id : hal-02185481 , version 1
  • PUBMED : 15822182

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Bertil B Fredholm, Jiang-Fan Chen, Susan A Masino, Jean-Marie Vaugeois. Actions of adenosine at its receptors in the CNS insights from knockouts and drugs. Annual Review of Pharmacology and Toxicology, 2005, 45, pp.385-412. ⟨hal-02185481⟩
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