Aggregation of amphiphilic pullulan derivatives evidenced by on-line flow field flow fractionation/multi-angle laser light scattering - Normandie Université Access content directly
Journal Articles Journal of Chromatography B Biomedical Sciences and Applications Year : 2001

Aggregation of amphiphilic pullulan derivatives evidenced by on-line flow field flow fractionation/multi-angle laser light scattering

D. Duval
  • Function : Author
  • PersonId : 833935
D. Le Cerf
L. Picton

Abstract

Size-exclusion chromatography (SEC) is a useful steric separation technique for the analysis of water-soluble polysaccharides in aqueous solution. However, in the case of amphiphilic derivatives, the usefulness is limited because of interactions between hydrophobic segments and the stationary phase. Alkyl-bearing pullulans differing from the extent and the length of alkyl groups were characterized using flow-field flow fractionation with on-line coupling multi-angle laser light scattering (F4/MALLS). Comparison of SEC and F4 is presented and the interest of F4 in the field of amphiphilic derivatives is demonstrated.
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Dates and versions

hal-01866916 , version 1 (03-09-2018)

Identifiers

  • HAL Id : hal-01866916 , version 1
  • PUBMED : 11302436

Cite

D. Duval, D. Le Cerf, L. Picton, G. Muller. Aggregation of amphiphilic pullulan derivatives evidenced by on-line flow field flow fractionation/multi-angle laser light scattering. Journal of Chromatography B Biomedical Sciences and Applications, 2001, 753 (1), pp.115-22. ⟨hal-01866916⟩
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