Isolation and Characterization of a Monoclonal Antibody Specific for Fibrinogen and Fibrin of Human Origin. - Normandie Université Access content directly
Journal Articles Thrombosis Research Year : 1983

Isolation and Characterization of a Monoclonal Antibody Specific for Fibrinogen and Fibrin of Human Origin.

Abstract

A hybridoma cell line secreting a monoclonal antibody directed against human fibrinogen has been isolated. The antigenic determinant recognized is present on both the fibrinogen and fibrin molecules but is apparently absent from the D and E fragments and from fibrinopeptides A and B. The antibody seems to recognize a conformational structure present in native fibrinogen and in which several or possibly all the fibrinogen polypeptide chains may participate.

Dates and versions

hal-01762072 , version 1 (09-04-2018)

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Brigitte Sola, Avner Pr, Zilber Mt, Connan F, D. Lévy. Isolation and Characterization of a Monoclonal Antibody Specific for Fibrinogen and Fibrin of Human Origin.. Thrombosis Research, 1983, ⟨10.1016/0049-3848(83)90219-0⟩. ⟨hal-01762072⟩

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