IS 1675 , a Novel Lactococcal Insertion Element, Forms a Transposon-Like Structure Including the Lacticin 481 Lantibiotic Operon - Normandie Université Accéder directement au contenu
Article Dans Une Revue (Data Paper) Journal of Bacteriology Année : 2000

IS 1675 , a Novel Lactococcal Insertion Element, Forms a Transposon-Like Structure Including the Lacticin 481 Lantibiotic Operon

Résumé

ABSTRACT Two copies of IS 1675 , a novel lactococcal insertion element from the IS 4 family, are present on a 70-kb plasmid, where they frame the lantibiotic lacticin 481 operon. The whole structure could be a composite transposon designated Tn 5721 . This study shows that the lacticin 481 operon does not include any regulatory gene and provides a new example of a transposon-associated bacteriocin determinant. We identified five other IS 1675 copies not associated with the lacticin 481 operon. The conservation of IS 1675 flanking sequences suggested a 24-bp target site.

Dates et versions

hal-04157202 , version 1 (10-07-2023)

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Citer

Alain Dufour, Alain Rincé, Patricia Uguen, Jean-Paul Le Pennec. IS 1675 , a Novel Lactococcal Insertion Element, Forms a Transposon-Like Structure Including the Lacticin 481 Lantibiotic Operon. Journal of Bacteriology, 2000, 182 (19), pp.5600-5605. ⟨10.1128/JB.182.19.5600-5605.2000⟩. ⟨hal-04157202⟩
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