Optimization of Organic Molecule Separation and Detection Using Gas Chromatographic Column Based on MEMS Technologies Developed for Planetary and Exobiology Studies - Normandie Université Access content directly
Conference Papers Year : 2022

Optimization of Organic Molecule Separation and Detection Using Gas Chromatographic Column Based on MEMS Technologies Developed for Planetary and Exobiology Studies

Arnaud Philippart
  • Function : Speaker
  • PersonId : 1222189
Cyril Szopa
Malak Bigourd
Valerie Agasse
Pascal Cardinael

Abstract

The work presented here aimed to explore functionalization and characterization of square cross section channels of microchip columns for on board instruments for organic molecule measurements in solar system. First, the influence of the analytical set-up used to integrate our microchips have been demonstrated and optimized to ensure the most real microchip performances and limit extra-column effects. Thus, several junction capillaries, liner internal diameter and detector parameters were compared and the best combination was chosen. Then, the influence of stationary phase static coating method parameters was studied by varying the coating velocity and the coating thickness. Efficiency measurement and optical microscopy were used to compare microchips. Results showed that slowing down the coating velocity improved the coating. Moreover, the efficiency and the retention capacity of our microchips highly depend on the film thickness (10,000 ptx.m-a with k = 0.12 for the thinnest film up to almost 5,000 ptx.m-a with k = 0.93 for the thickest film) and varied following the same trend as with conventional GC columns, which is a way to validate our coating method on microchips. Finally, we compared square cross section and circular cross section and both using conventional GC fused silica capillaries. Result demonstrated the anticipated complications of coating a stationary phase film on a square cross section
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Dates and versions

hal-03967957 , version 1 (01-02-2023)

Identifiers

  • HAL Id : hal-03967957 , version 1

Cite

Arnaud Philippart, Cyril Szopa, Malak Bigourd, Valerie Agasse, Guillaume Rioland, et al.. Optimization of Organic Molecule Separation and Detection Using Gas Chromatographic Column Based on MEMS Technologies Developed for Planetary and Exobiology Studies. 33rd international symposium on chromatography (ISC), Sep 2022, Budapest, Hungary. ⟨hal-03967957⟩
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