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Journal Articles Crystals Year : 2022

Behavior of B- and Z-DNA Crystals under High Hydrostatic Pressure

Abstract

Single crystals of B-DNA and Z-DNA oligomers were analyzed under high hydrostatic pressure and their behavior compared to the A-DNA crystals already known. The amplitude of the base compression, when compared to the A-form of DNA (0.13 Å/GPa), was higher for the Z DNA (0.32 Å/GPa) and was the highest for the B-DNA (0.42 Å/GPa). The B-DNA crystal degraded rapidly around 400-500 MPa while the Z-structure was more resistant, up to 1.2 GPa.
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hal-03781069 , version 1 (20-09-2022)

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Thierry Prangé, Nathalie Colloc’h, Anne-Claire Dhaussy, Marc Lecouvey, Evelyne Migianu-Griffoni, et al.. Behavior of B- and Z-DNA Crystals under High Hydrostatic Pressure. Crystals, 2022, 12 (6), pp.871. ⟨10.3390/cryst12060871⟩. ⟨hal-03781069⟩
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