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authFullName_s : Julien Renou

Potent 3‐Hydroxy‐2‐Pyridine Aldoxime Reactivators of Organophosphate‐Inhibited Cholinesterases with Predicted Blood–Brain Barrier Penetration

Tamara Zorbaz , Anissa Braïki , Nikola Marakovic , Julien Renou , Eugenio de La Mora , et al.
Chemistry - A European Journal, 2018, 24 (38), pp.9675-9691. ⟨10.1002/chem.201801394⟩
Journal articles hal-02024542v1

Reactivators of acetylcholinesterase inhibited by organophosphorus nerve agents

Guillaume Mercey , Tristan Verdelet , Julien Renou , Maria Kliachyna , Rachid Baati , et al.
Accounts of Chemical Research, 2012, 45 (5), pp.756-766. ⟨10.1021/ar2002864⟩
Journal articles hal-01015972v1

Design, synthesis and biological evaluation of novel tetrahydroacridine pyridine- aldoxime and -amidoxime hybrids as efficient uncharged reactivators of nerve agent-inhibited human acetylcholinesterase

Maria Kliachyna , Gianluca Santoni , Valentin Nussbaum , Julien Renou , Benoît Sanson , et al.
European Journal of Medicinal Chemistry, 2014, 78, pp.455-467. ⟨10.1016/j.ejmech.2014.03.044⟩
Journal articles hal-01131268v1

Synthesis and in vitro and in vivo evaluations of New Uncharged reactivators for cholinesterases inhibited by organophosphorus nerve agents

Anissa Braïki , Julien Renou , Romain Mougeot , Florian Nachon , José Dias , et al.
Medical Chemical Defense Conference (MCDC, 17, 2019), Mar 2019, Munich, Germany
Conference poster hal-02543452v1

Tryptoline-​3-​hydroxypyridinaldoxime conjugates as efficient reactivators of phosphylated human acetyl and butyrylcholinesterase

Julien Renou , Melanie Loiodice , Melanie Arboleas , Rachid Baati , Ludovic Jean , et al.
Chemical Communications, 2014, 50 (30), pp.3947-3950. ⟨10.1039/C4CC00561A⟩
Journal articles hal-01150284v1

Syntheses and in vitro evaluations of uncharged reactivators for human acetylcholinesterase inhibited by organophosphorus nerve agents.

Julien Renou , Guillaume Mercey , Tristan Verdelet , Emilia Păunescu , Emilie Gillon , et al.
Chemico-Biological Interactions, 2013, 203 (1), pp.81-84. ⟨10.1016/j.cbi.2012.09.023⟩
Journal articles hal-00996535v1

Synthesis and in vitro evaluation of donepezil-based reactivators and analogues for nerve agent-inhibited human acetylcholinesterase

Julien Renou , José Dias , Guillaume Mercey , Tristan Verdelet , Catherine Rousseau , et al.
RSC Advances, 2016, 6 (22), pp.17929-17940. ⟨10.1039/c5ra25477a⟩
Journal articles hal-02046237v1

Uncharged reactivators of cholinesterases inhibited by organophosphorus nerve agents.

Nicolas Probst , Anissa Braïki , Pierre Warnault , Julien Renou , Catherine Gomez , et al.
International Meeting on Cholinesterases (13, 2018) and International Conference on Paraoxonases (7, 2018)), Sep 2018, Hradec Králové, Czech Republic
Conference poster hal-02543467v1

New Uncharged reactivators for cholinesterases inhibited by organophosphorus nerve agents

Anissa Braïki , Julien Renou , Romain Mougeot , Tamara Zorbaz , André-Guilhem Calas , et al.
International Conference on Chemical Biological Radiological nuclear Explosive - Research & Innovation (CBRNE, 2, 2017), May 2017, Lyon, France
Conference poster hal-02544823v1

Design and Development of New Uncharged Reactivators of OP-Inhibited Cholinesterases

Pierre Warnault , Julien Renou , Catherine Gomez , Guillaume Mercey , Tristan Verdelet , et al.
International Conference on Chemical Biological Radiological and Nuclear agents (CBRN) - Research & Innovation (1, 2015), Mar 2015, Antibes, France
Conference poster hal-02544917v1

Phenyltetrahydroisoquinoline-pyridinaldoxime conjugates as efficient uncharged reactivators for the dephosphylation of inhibited human acetylcholinesterase.

Guillaume Mercey , Julien Renou , Tristan Verdelet , Maria Kliachyna , Rachid Baati , et al.
Journal of Medicinal Chemistry, 2012, 55 (23), pp.10791-10795. ⟨10.1021/jm3015519⟩
Journal articles hal-00996512v1

A miniaturized peptidyl-prolyl isomerase enzyme assay

Mirella Vivoli , Julien Renou , Arnaud Chevalier , Isobel H. Norville , Suraya Diaz , et al.
Analytical Biochemistry, 2017, 536, pp.59-68. ⟨10.1016/j.ab.2017.08.004⟩
Journal articles hal-02046314v1

Synthesis and evaluations of uncharged reactivators for cholinesterases inhibited by organophosphate agents

Anissa Braïki , Julien Renou , Romain Mougeot , Florian Nachon , André-Guilhem Calas , et al.
International Conference on Chemical Biological Radiological and Nuclear agents (CBRN) - Research & Innovation (3, 2019), May 2019, Nantes, France
Conference poster hal-02543439v1

Novel uncharged reactivators against OP-inhibition of human acetylcholinesterase

Rachid Baati , Maria Klyachina , Valentin Nussbaum , Pierre-Yves Renard , Ludovic Jean , et al.
France, Patent n° : EP13306584.7. 2013
Patents hal-01150304v1

Synthesis of new uncharged reactivators for cholinesterases inhibited by organophosphorus nerve agents

Anissa Braïki , Julien Renou , Catherine Gomez , Romain Mougeot , Florian Nachon , et al.
Tetrahedron Symposium (17, 2016), Jun 2016, Barcelone, Spain
Conference poster hal-02544884v1

Uncharged Reactivators of cholinesterases Inhibited by organophosphorus nerve agents

Pierre Warnault , Julien Renou , Catherine Gomez , Guillaume Mercey , Tristan Verdelet , et al.
International Meeting on Cholinesterases - Sixth International Conference on Paraoxonases (12, 2015), Sep 2015, Elche, Spain
Conference poster hal-02544902v1