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                <title xml:lang="en">Effects of different exercise training program on post-exercise V̇O 2 kinetics and V̇O 2 recovery delay in stable patients with coronary heart disease</title>
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              <p>Abstract Post-exercise V̇O 2 kinetics and V̇O 2 recovery delay (RD) are clinical prognostic markers in cardiac patients, but have not been studied after exercise training in patients with coronary heart disease (CHD). We aimed to compare the effects of 12-weeks moderate-intensity continuous exercise training (MICET), low volume high-intensity interval training (LV-HIIT), or combined MICET/HIIT on O 2 deficit, post-exercise V̇O 2 kinetics, O 2 debt and V̇O 2 recovery delay (RD) in patients with CHD. Methods Patients with CHD were randomised in MICET, LV-HIIT or combined MICET/HIIT group for 12 weeks. Cardiopulmonary exercise test (CPET) parameters were assessed, and key exercise variables were calculated during and after exercise. CPET post-exercise kinetics time constant (r) (for V̇O 2 , V̇CO 2 , V̇ E and HR), O 2 deficit, O 2 debt and V̇O 2 recovery delay (RD) were calculated before and after training. Results A significant time effect (training) for r V̇O 2 (min) (p&amp;lt;0.05) was shown for all groups. Shorter r V̇O 2 values with small effect size (ES: 0.21 to 0.4) were noted for the combined MICET/HIIT and MICET groups. A significant time effect (p&amp;lt;0.01) was noted for O 2 debt that was increased after training (ES: 0.1 to 0.47). No significant statistical effect was shown for V̇O 2 RD and r V̇CO 2 , r V̇ E, r HR and O 2 deficit in all groups. Conclusions In patients with CHD, exercise training improved post-exercise V̇O 2 kinetic and the O 2 debt, with a higher impact of exercise dose (combined MICET/HIIT). Exercise training did not improved the V̇O 2 RD or other τ CPET recovery variables in CHD patients.</p>
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