Article Dans Une Revue AJP - Gastrointestinal and Liver Physiology Année : 2025

Dynamic functional luminal imaging probe analysis of the anal sphincter opening function during straining in healthy volunteers

Résumé

In the present study, we generated a bioinformatics pipeline for analyzing anal EndoFLIP data in healthy volunteers using automated data reprocessing to identify potential markers of anal opening function during the push maneuver. Mean relative variations in pressure and CSA at 50 mL of distension were identified as the most indicative parameters. Given that this was a pilot study, our findings warrant further confirmatory research to establish the clinical relevance of these markers.

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Dates et versions

hal-05049713 , version 1 (28-04-2025)

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Charlotte Desprez, Anne-Marie Leroi, Guillaume Gourcerol, Ali Zifan, Thomas Duflot. Dynamic functional luminal imaging probe analysis of the anal sphincter opening function during straining in healthy volunteers. AJP - Gastrointestinal and Liver Physiology, 2025, 328 (5), pp.G513-G521. ⟨10.1152/ajpgi.00369.2024⟩. ⟨hal-05049713⟩
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