20.2.11.2 Alk-2-enoic Acids (Update 2024)
Résumé
Abstract The α, β-unsaturated carboxylic acid motif stands out for its versatility and utility in constructing complex molecular structures, spanning pharmaceuticals to natural products. This review describes the published methods for the synthesis of alk-2-enoic acids reported between 2007 and 2023. It is an update to the original Science of Synthesis review (Section 20.2.11), published in 2007. The focus lies on novel synthetic approaches facilitating the incorporation of the α, β-unsaturated carboxylic acid motif from a range of starting materials, including diversely functionalized or unfunctionalized alcohols, aldehydes, ketones, alkenes, and alkynes.
Domaines
Chimie organiqueOrigine | Fichiers produits par l'(les) auteur(s) |
---|