Discovery of a Potent Dual Inhibitor of Acetylcholinesterase and Butyrylcholinesterase with Antioxidant Activity that Alleviates Alzheimer-like Pathology in Old APP/PS1 Mice

Elisabet Viayna; Nicolas Coquelle; Monika Cieslikiewicz-Bouet; Pedro Cisternas; Carolina Oliva; Elena Sánchez-López; Miren Ettcheto; Manuela Bartolini; Angela de Simone; Mattia Ricchini; Marisa Rendina; Mégane Pons; Omidreza Firuzi; Belén Pérez; Luciano Saso; Vincenza Andrisano; Florian Nachon; Xavier Brazzolotto; Maria Luisa García; Antoni Camins; Israel Silman; Ludovic Jean; Nibaldo Inestrosa; Jacques-Philippe Colletier; Pierre-Yves Renard; Diego Muñoz-Torrero

doi:10.1021/acs.jmedchem.0c01775

Journal Articles Journal of Medicinal Chemistry Year : 2020

Discovery of a Potent Dual Inhibitor of Acetylcholinesterase and Butyrylcholinesterase with Antioxidant Activity that Alleviates Alzheimer-like Pathology in Old APP/PS1 Mice

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1
2

Elisabet Viayna

Function : Author

Nicolas Coquelle

Function : Author

Institut de biologie structurale

Monika Cieslikiewicz-Bouet

Function : Author
PersonId : 791780
IdHAL : monika-bouet
ORCID : 0000-0002-0783-1590

Pedro Cisternas

Function : Author

Carolina Oliva

Function : Author

Elena Sánchez-López

Function : Author

Miren Ettcheto

Function : Author

Manuela Bartolini

Function : Author
PersonId : 791781
ORCID : 0000-0002-2890-3856

Angela de Simone

Function : Author

Mattia Ricchini

Function : Author

Marisa Rendina

Function : Author

Mégane Pons

Function : Author

Omidreza Firuzi

Function : Author

Belén Pérez

Function : Author

Luciano Saso

Function : Author

Vincenza Andrisano

Function : Author
PersonId : 805015
ORCID : 0000-0003-4396-1904

Florian Nachon

Function : Author
PersonId : 765718
ORCID : 0000-0003-0293-2429
IdRef : 138014787

Xavier Brazzolotto

Function : Author

Maria Luisa García

Function : Author

Antoni Camins

Function : Author

Israel Silman

Function : Author

Ludovic Jean

Function : Author
PersonId : 177141
IdHAL : ludovic-jean
ORCID : 0000-0002-1745-4952
IdRef : 084305495

Chimie Organique et Bioorganique : Réactivité et Analyse

Nibaldo Inestrosa

Function : Author

Jacques-Philippe Colletier

Function : Author
PersonId : 739662
IdHAL : jacques-philippe-colletier
ORCID : 0000-0003-1819-4686
IdRef : 110264983

Institut de biologie structurale

Pierre-Yves Renard

Function : Author
PersonId : 178108
IdHAL : pierre-yves-renard
ORCID : 0000-0001-9094-9778
IdRef : 122924029

CV

Diego Muñoz-Torrero

Function : Author

Domains

Chemical Sciences Organic chemistry Medicinal Chemistry

Ludovic JEAN : Connect in order to contact the contributor

https://normandie-univ.hal.science/hal-03094189

Submitted on : Monday, January 4, 2021-11:35:38 AM

Last modification on : Wednesday, December 18, 2024-9:37:18 AM

Dates and versions

hal-03094189 , version 1 (04-01-2021)

Identifiers

HAL Id : hal-03094189 , version 1
DOI : 10.1021/acs.jmedchem.0c01775

Cite

Elisabet Viayna, Nicolas Coquelle, Monika Cieslikiewicz-Bouet, Pedro Cisternas, Carolina Oliva, et al.. Discovery of a Potent Dual Inhibitor of Acetylcholinesterase and Butyrylcholinesterase with Antioxidant Activity that Alleviates Alzheimer-like Pathology in Old APP/PS1 Mice. Journal of Medicinal Chemistry, 2020, ⟨10.1021/acs.jmedchem.0c01775⟩. ⟨hal-03094189⟩

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Discovery of a Potent Dual Inhibitor of Acetylcholinesterase and Butyrylcholinesterase with Antioxidant Activity that Alleviates Alzheimer-like Pathology in Old APP/PS1 Mice

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