<?xml version="1.0" encoding="utf-8"?>
<TEI xmlns="http://www.tei-c.org/ns/1.0" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:hal="http://hal.archives-ouvertes.fr/" xmlns:gml="http://www.opengis.net/gml/3.3/" xmlns:gmlce="http://www.opengis.net/gml/3.3/ce" version="1.1" xsi:schemaLocation="http://www.tei-c.org/ns/1.0 http://api.archives-ouvertes.fr/documents/aofr-sword.xsd">
  <teiHeader>
    <fileDesc>
      <titleStmt>
        <title>HAL TEI export of hal-02296506</title>
      </titleStmt>
      <publicationStmt>
        <distributor>CCSD</distributor>
        <availability status="restricted">
          <licence target="https://creativecommons.org/publicdomain/zero/1.0/">CC0 1.0 - Universal</licence>
        </availability>
        <date when="2026-05-19T06:20:40+02:00"/>
      </publicationStmt>
      <sourceDesc>
        <p part="N">HAL API Platform</p>
      </sourceDesc>
    </fileDesc>
  </teiHeader>
  <text>
    <body>
      <listBibl>
        <biblFull>
          <titleStmt>
            <title xml:lang="en">Oyster sex determination is influenced by temperature — First clues in spat during first gonadic differentiation and gametogenesis</title>
            <author role="aut">
              <persName>
                <forename type="first">Christelle</forename>
                <surname>Santerre</surname>
              </persName>
              <idno type="halauthorid">1658214-0</idno>
              <affiliation ref="#struct-267921"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Pascal</forename>
                <surname>Sourdaine</surname>
              </persName>
              <email type="md5">9c2505277be17e502f7680a5e8abc914</email>
              <email type="domain">unicaen.fr</email>
              <idno type="idhal" notation="string">pascal-sourdaine</idno>
              <idno type="idhal" notation="numeric">739449</idno>
              <idno type="halauthorid" notation="string">10722-739449</idno>
              <idno type="IDREF">https://www.idref.fr/069283532</idno>
              <idno type="ORCID">https://orcid.org/0000-0001-9811-2876</idno>
              <affiliation ref="#struct-267921"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Nicolas</forename>
                <surname>Marc</surname>
              </persName>
              <email type="md5">95fcfbf92ce1e02a44e6d2e3ec735586</email>
              <email type="domain">wanadoo.fr</email>
              <idno type="idhal" notation="numeric">960328</idno>
              <idno type="halauthorid" notation="string">862051-960328</idno>
              <affiliation ref="#struct-300022"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Christian</forename>
                <surname>Mingant</surname>
              </persName>
              <idno type="halauthorid">948583-0</idno>
              <affiliation ref="#struct-300022"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">René</forename>
                <surname>Robert</surname>
              </persName>
              <email type="md5">5d78cc1aba124e95ff13e505a92e4e26</email>
              <email type="domain">chu-poitiers.fr</email>
              <idno type="idhal" notation="numeric">920024</idno>
              <idno type="halauthorid" notation="string">615446-920024</idno>
              <affiliation ref="#struct-300022"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Anne-Sophie</forename>
                <surname>Martinez</surname>
              </persName>
              <idno type="halauthorid">1658215-0</idno>
              <affiliation ref="#struct-267921"/>
            </author>
            <editor role="depositor">
              <persName>
                <forename>Pascal</forename>
                <surname>SOURDAINE</surname>
              </persName>
              <email type="md5">9c2505277be17e502f7680a5e8abc914</email>
              <email type="domain">unicaen.fr</email>
            </editor>
          </titleStmt>
          <editionStmt>
            <edition n="v1" type="current">
              <date type="whenSubmitted">2019-09-25 11:41:53</date>
              <date type="whenModified">2024-01-24 08:26:10</date>
              <date type="whenReleased">2019-09-25 11:41:53</date>
              <date type="whenProduced">2013-05</date>
              <ref type="externalLink" target="https://archimer.ifremer.fr/doc/00136/24767/22874.pdf"/>
            </edition>
            <respStmt>
              <resp>contributor</resp>
              <name key="16250">
                <persName>
                  <forename>Pascal</forename>
                  <surname>SOURDAINE</surname>
                </persName>
                <email type="md5">9c2505277be17e502f7680a5e8abc914</email>
                <email type="domain">unicaen.fr</email>
              </name>
            </respStmt>
          </editionStmt>
          <publicationStmt>
            <distributor>CCSD</distributor>
            <idno type="halId">hal-02296506</idno>
            <idno type="halUri">https://normandie-univ.hal.science/hal-02296506</idno>
            <idno type="halBibtex">santerre:hal-02296506</idno>
            <idno type="halRefHtml">&lt;i&gt;Comparative Biochemistry and Physiology - Part A: Molecular and Integrative Physiology&lt;/i&gt;, 2013, 165 (1), pp.61-69. &lt;a target="_blank" href="https://dx.doi.org/10.1016/j.cbpa.2013.02.007"&gt;&amp;#x27E8;10.1016/j.cbpa.2013.02.007&amp;#x27E9;&lt;/a&gt;</idno>
            <idno type="halRef">Comparative Biochemistry and Physiology - Part A: Molecular and Integrative Physiology, 2013, 165 (1), pp.61-69. &amp;#x27E8;10.1016/j.cbpa.2013.02.007&amp;#x27E9;</idno>
            <availability status="restricted"/>
          </publicationStmt>
          <seriesStmt>
            <idno type="stamp" n="CNRS">CNRS - Centre national de la recherche scientifique</idno>
            <idno type="stamp" n="IFREMER">IFREMER : Institut français de recherche pour l'exploitation de la mer</idno>
            <idno type="stamp" n="COMUE-NORMANDIE">Normandie Université</idno>
            <idno type="stamp" n="UNICAEN">Université de Caen Normandie</idno>
          </seriesStmt>
          <notesStmt>
            <note type="audience" n="2">International</note>
            <note type="popular" n="0">No</note>
            <note type="peer" n="1">Yes</note>
          </notesStmt>
          <sourceDesc>
            <biblStruct>
              <analytic>
                <title xml:lang="en">Oyster sex determination is influenced by temperature — First clues in spat during first gonadic differentiation and gametogenesis</title>
                <author role="aut">
                  <persName>
                    <forename type="first">Christelle</forename>
                    <surname>Santerre</surname>
                  </persName>
                  <idno type="halauthorid">1658214-0</idno>
                  <affiliation ref="#struct-267921"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Pascal</forename>
                    <surname>Sourdaine</surname>
                  </persName>
                  <email type="md5">9c2505277be17e502f7680a5e8abc914</email>
                  <email type="domain">unicaen.fr</email>
                  <idno type="idhal" notation="string">pascal-sourdaine</idno>
                  <idno type="idhal" notation="numeric">739449</idno>
                  <idno type="halauthorid" notation="string">10722-739449</idno>
                  <idno type="IDREF">https://www.idref.fr/069283532</idno>
                  <idno type="ORCID">https://orcid.org/0000-0001-9811-2876</idno>
                  <affiliation ref="#struct-267921"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Nicolas</forename>
                    <surname>Marc</surname>
                  </persName>
                  <email type="md5">95fcfbf92ce1e02a44e6d2e3ec735586</email>
                  <email type="domain">wanadoo.fr</email>
                  <idno type="idhal" notation="numeric">960328</idno>
                  <idno type="halauthorid" notation="string">862051-960328</idno>
                  <affiliation ref="#struct-300022"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Christian</forename>
                    <surname>Mingant</surname>
                  </persName>
                  <idno type="halauthorid">948583-0</idno>
                  <affiliation ref="#struct-300022"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">René</forename>
                    <surname>Robert</surname>
                  </persName>
                  <email type="md5">5d78cc1aba124e95ff13e505a92e4e26</email>
                  <email type="domain">chu-poitiers.fr</email>
                  <idno type="idhal" notation="numeric">920024</idno>
                  <idno type="halauthorid" notation="string">615446-920024</idno>
                  <affiliation ref="#struct-300022"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Anne-Sophie</forename>
                    <surname>Martinez</surname>
                  </persName>
                  <idno type="halauthorid">1658215-0</idno>
                  <affiliation ref="#struct-267921"/>
                </author>
              </analytic>
              <monogr>
                <idno type="halJournalId" status="VALID">11943</idno>
                <idno type="issn">1095-6433</idno>
                <title level="j">Comparative Biochemistry and Physiology - Part A: Molecular and Integrative Physiology</title>
                <imprint>
                  <publisher>Elsevier</publisher>
                  <biblScope unit="volume">165</biblScope>
                  <biblScope unit="issue">1</biblScope>
                  <biblScope unit="pp">61-69</biblScope>
                  <date type="datePub">2013-05</date>
                </imprint>
              </monogr>
              <idno type="doi">10.1016/j.cbpa.2013.02.007</idno>
            </biblStruct>
          </sourceDesc>
          <profileDesc>
            <langUsage>
              <language ident="en">English</language>
            </langUsage>
            <textClass>
              <keywords scheme="author">
                <term xml:lang="en">Oyster spat</term>
                <term xml:lang="en">Sex determination pathway</term>
                <term xml:lang="en">TSD</term>
                <term xml:lang="en">Sex ratio</term>
                <term xml:lang="en">Temperature</term>
              </keywords>
              <classCode scheme="halDomain" n="sdv">Life Sciences [q-bio]</classCode>
              <classCode scheme="halTypology" n="ART">Journal articles</classCode>
              <classCode scheme="halOldTypology" n="ART">Journal articles</classCode>
              <classCode scheme="halTreeTypology" n="ART">Journal articles</classCode>
            </textClass>
            <abstract xml:lang="en">
              <p>The sex-determining system of Crassostrea gigas is still poorly known, especially regarding the potential influence of temperature. In order to address this question, mRNA expressions of actors of the molecular cascade (Cg-DMl, Cg-SoxE, Cg-β-catenin, Cg-Foxl2/Cg-Foxl2os) and of Oyvlg, a germ cell marker, were investigated by real-time PCR in spat grown at different temperatures (18, 22, 25 and 28 °C). In parallel, gonadic differentiation, gametogenesis and sex ratios were assessed by histology at each of these temperatures. Whatever the temperature, Cg-DMl, Cg-SoxE, Cg-β-catenin and Oyvlg expressions peaked at the same developmental stage, always after Cg-Foxl2/Cg-Foxl2os (around 40–44 dpf for spat grown at 18 °C). Temperatures increased the kinetics of first gonadic differentiation and gametogenesis. At 25 °C a significant switch occurred in sex ratio towards males and in the balance of expression between male and female genes, in favor of males. A slight gametogenesis disturbance was also observed. These results strengthen the hypotheses about the sex-determining time window and molecular cascade governing the development of C. gigas, with notably the involvement of Cg-Foxl2/Cg-Foxl2os in the very early steps. They also suggest an influence of temperature on the oyster's sex determination which, associated to genetic control, would induce a mixed sex determination system (GSD + TSD).</p>
            </abstract>
          </profileDesc>
        </biblFull>
      </listBibl>
    </body>
    <back>
      <listOrg type="structures">
        <org type="laboratory" xml:id="struct-267921" status="OLD">
          <idno type="IdRef">184555752</idno>
          <idno type="RNSR">201220076Z</idno>
          <orgName>Biologie des mollusques marins et des écosystèmes associés</orgName>
          <orgName type="acronym">BioMEA</orgName>
          <date type="start">2012-01-01</date>
          <date type="end">2013-12-31</date>
          <desc>
            <address>
              <addrLine>Esplanade de la paix 14032 CAEN CEDEX 5</addrLine>
              <country key="FR"/>
            </address>
          </desc>
          <listRelation>
            <relation active="#struct-7127" type="direct"/>
            <relation active="#struct-455934" type="indirect"/>
            <relation name="FRE3484" active="#struct-441569" type="direct"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-300022" status="VALID">
          <idno type="IdRef">027783073</idno>
          <idno type="ISNI">0000000121634107</idno>
          <idno type="ROR">https://ror.org/044jxhp58</idno>
          <orgName>Institut Français de Recherche pour l'Exploitation de la Mer</orgName>
          <orgName type="acronym">IFREMER</orgName>
          <date type="start">1984-01-01</date>
          <desc>
            <address>
              <country key="FR"/>
            </address>
            <ref type="url">https://wwz.ifremer.fr/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-7127" status="VALID">
          <idno type="IdRef">026403064</idno>
          <idno type="ISNI">0000000121864076</idno>
          <idno type="ROR">https://ror.org/051kpcy16</idno>
          <orgName>Université de Caen Normandie</orgName>
          <orgName type="acronym">UNICAEN</orgName>
          <date type="start">1432-01-01</date>
          <desc>
            <address>
              <addrLine>Esplanade de la Paix - CS 14032 - 14032 CAEN Cedex 5</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.unicaen.fr/</ref>
          </desc>
          <listRelation>
            <relation active="#struct-455934" type="direct"/>
          </listRelation>
        </org>
        <org type="regroupinstitution" xml:id="struct-455934" status="VALID">
          <idno type="IdRef">190906332</idno>
          <idno type="ISNI">0000000417859671 </idno>
          <idno type="ROR">https://ror.org/01k40cz91</idno>
          <orgName>Normandie Université</orgName>
          <orgName type="acronym">NU</orgName>
          <date type="start">2015-01-01</date>
          <desc>
            <address>
              <addrLine>Esplanade de la Paix - CS 14032 - 14032 Caen Cedex 5</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.normandie-univ.fr/</ref>
          </desc>
        </org>
        <org type="regroupinstitution" xml:id="struct-441569" status="VALID">
          <idno type="IdRef">02636817X</idno>
          <idno type="ISNI">0000000122597504</idno>
          <idno type="ROR">https://ror.org/02feahw73</idno>
          <orgName>Centre National de la Recherche Scientifique</orgName>
          <orgName type="acronym">CNRS</orgName>
          <date type="start">1939-10-19</date>
          <desc>
            <address>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.cnrs.fr/</ref>
          </desc>
        </org>
      </listOrg>
    </back>
  </text>
</TEI>