Efficient Microwave-Assisted Synthesis of Methyl 4- or 5-Nitro­anthranilate - Normandie Université Access content directly
Journal Articles Synthesis: Journal of Synthetic Organic Chemistry Year : 2016

Efficient Microwave-Assisted Synthesis of Methyl 4- or 5-Nitro­anthranilate

Abstract

A novel method for the synthesis of anthranilate esters is described. The esterification reaction of nitro-substituted anthranilic acids was carried out under microwave irradiation. A range of solvents and other reaction parameters were investigated to provide the most environmentally friendly reaction conditions. The feasibility of scale-up was demonstrated, allowing a simple and inexpensive production of anthranilate esters.
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hal-02046207 , version 1 (22-02-2019)

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Julien Godeau, Anthony Martinet, Vincent Levacher, Corinne Fruit, Thierry Besson. Efficient Microwave-Assisted Synthesis of Methyl 4- or 5-Nitro­anthranilate. Synthesis: Journal of Synthetic Organic Chemistry, 2016, 48 (20), pp.3504-3508. ⟨10.1055/s-0035-1562484⟩. ⟨hal-02046207⟩
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